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Utilization of 3D Printing for Biomanufacturing

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  • access_time 11:00 - 11:55 AM CT
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Biomanufacturing is one of the fastest growing advanced manufacturing modalities in the world. This highly regulated field supports a 500-billion-dollar market and shows significant potential for applying additive manufacturing techniques for single-use flow path development, manufacturing flexibility and other applications that can reduce the cost of goods.

Currently, 3D printing is only used for unsophisticated solutions such as brackets, holders, and other non-product contact parts. In this talk we will discuss how advanced additive manufacturing techniques can be utilized in biomanufacturing assemblies, as well as showcase several applications. These applications have the potential to revolutionize chromatography techniques used for continuous purification of life saving modalities such as monoclonal antibodies and gene therapies.

Additive manufacturing creates a design space for geometrically complex flow cells that cannot be manufactured with standard processes like CNC milling, injection molding or PDMS fabrication. In this talk we will demonstrate microfluidic devices that were used to efficiently separate chromatography resin particles using Dean Vortices, as well as custom-made flow path components that enable high productivity, residence time reduction and efficient space management. Finally, we will also discuss next generation applications for further implementation of sophisticated additive manufacturing such as DLP for single-use components with the eventual adoption into clinical / cGMP field.

Learning Objectives:

  • Understand that additive manufacturing allows new revolutionary biomanufacturing techniques to be utilized to improve the industry by increasing productivity while also decreasing development and production costs.
  • Describe how 3D printing can be utilized to design advanced microfluidic devices that cannot be created with traditional methods.
  • Discuss why 3D printing should be utilized more in the biomanufacturing industry.